Using w-shingling to group similar genes into metabuckets

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

The Pseudomonas aeruginosa AGI is an opportunistic superbug that affects patients with weakened immune systems due to infectious diseases in eyes, ears, burns or chronic diseases such as cystic flbrosis. This bacterium has genes without information and it is necessary to determine the function they fulfill in order to seek medical treatment that helps infected patients. Using w-shingling, metabuckets are generated that group genes by their similarity. Each metabucket contains genes with or without information, the latter can be associated with information about what they do possess. In addition, a factorial experiment is presented with the results of applying the algorithm to a set of genes obtained from public databases, where the average similarity of the genes grouped in metabuckets reaches 98%.

Original languageEnglish
Title of host publicationProceedings - 2019 45th Latin American Computing Conference, CLEI 2019
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781728155746
DOIs
StatePublished - Sep 2019
Event45th Latin American Computing Conference, CLEI 2019 - Panama City, Panama
Duration: 30 Sep 20194 Oct 2019

Publication series

NameProceedings - 2019 45th Latin American Computing Conference, CLEI 2019

Conference

Conference45th Latin American Computing Conference, CLEI 2019
Country/TerritoryPanama
CityPanama City
Period30/09/194/10/19

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • factorial experiment
  • genes,
  • Metabucket
  • Pseudomona aeruginosa,
  • similarity
  • w-shingling

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