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In vitro biocompatibility study and electrical properties O T E PEDOT PEDOT collagen coat PEDOT nanotubes and PEDOT aerogels for neural electrodes

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

The aim of this study is to evaluate the cytotoxicity of Poly(3, 4-ethylenedioxythiophene) (PEDOT), PEDOT-collagen and PEDOT nanostructured coatings for neural electrodes. Incorporation of cell growth factors and the structuration of supporting material are two strategies to improve cell adhesion and biocompatibility in order to produce better and more specific neural implants. PEDOT coat, PEDOT-collagen coat, PEDOT nanotubes and PEDOT aerogel were tested for biocompability using the standard ISO 10993-5. PEDOT and PEDOT-Collagen coats were deposited via galvanostatic electropolymerization from a NaPSS micellar dispersion. In addition PEDOT nanotubes were obtained by hard polycarbonate template and PEDOT aerogels were chemically produced through a soft starch template. PEDOT samples were studied for biocompatibility, characterized by LCRmeter and Scanning electron microscopy (SEM). Biocompatibility test verified the absence of cytotoxic effects in all the PEDOT samples.

Original languageEnglish
Title of host publicationProceedings of the IASTED International Conference on Biomedical Engineering, BioMed 2013
Pages320-326
Number of pages7
DOIs
StatePublished - 2013
Externally publishedYes
Event10th IASTED International Conference on Biomedical Engineering, BioMed 2013 - Innsbruck, Austria
Duration: 13 Feb 201315 Feb 2013

Publication series

NameProceedings of the IASTED International Conference on Biomedical Engineering, BioMed 2013

Conference

Conference10th IASTED International Conference on Biomedical Engineering, BioMed 2013
Country/TerritoryAustria
CityInnsbruck
Period13/02/1315/02/13

Keywords

  • Aerogels
  • Bio-nanotechnology
  • Biocompatibility
  • Nanotubes
  • Neural engineering
  • PEDOT
  • Structuration

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