An Impedance spectroscopy ASIC for low-frequency characterization of biological samples

Juan J. Montero-Rodŕiguez; Edgar Eduardo Salazar-Fĺorez; Paola Vega-Castillo; Jakob M. Tomasik; Wjatscheslaw Galjan; Kristian M. Hafkemeyer; Wolfgang Krautschneider

doi:10.5220/0005772202220228

An Impedance spectroscopy ASIC for low-frequency characterization of biological samples

Juan J. Montero-Rodŕiguez
, Edgar Eduardo Salazar-Fĺorez
, Paola Vega-Castillo
, Jakob M. Tomasik
, Wjatscheslaw Galjan
, Kristian M. Hafkemeyer
, Wolfgang Krautschneider

Escuela de Ingeniería Electrónica

Hamburg University of Technology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Scopus citations

Abstract

This paper describes the design and testing of an ASIC for impedance spectroscopy of biological samples at frequencies up to 40 kHz. The circuit is designed in the 350 nm AMS H35B4 technology and enables the measurement of impedances in the range of 10 kΩ up to 28 MΩ. The design features a digital oscillator and a current-to-voltage converter. The ASIC is used to monitor the growth of yeast cell cultures and porcine chondrocytes, in real-time, using a standard 384-well plate and copper electrodes.

Original language	English
Title of host publication	BIODEVICES 2016 - 9th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016
Editors	James Gilbert, Haim Azhari, Hesham Ali, Carla Quintao, Jan Sliwa, Carolina Ruiz, Ana Fred, Hugo Gamboa
Publisher	SciTePress
Pages	222-228
Number of pages	7
ISBN (Electronic)	9789897581700
DOIs	https://doi.org/10.5220/0005772202220228
State	Published - 2016
Event	9th International Conference on Biomedical Electronics and Devices, BIODEVICES 2016 - Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016 - Rome, Italy Duration: 21 Feb 2016 → 23 Feb 2016

Publication series

Name	BIODEVICES 2016 - 9th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016

Conference

Conference	9th International Conference on Biomedical Electronics and Devices, BIODEVICES 2016 - Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016
Country/Territory	Italy
City	Rome
Period	21/02/16 → 23/02/16

Keywords

ASIC
Cell concentration
Impedance spectroscopy
Porcine chondrocytes
Yeast

Access to Document

10.5220/0005772202220228

Cite this

Montero-Rodŕiguez, J. J., Salazar-Fĺorez, E. E., Vega-Castillo, P., Tomasik, J. M., Galjan, W., Hafkemeyer, K. M., & Krautschneider, W. (2016). An Impedance spectroscopy ASIC for low-frequency characterization of biological samples. In J. Gilbert, H. Azhari, H. Ali, C. Quintao, J. Sliwa, C. Ruiz, A. Fred, & H. Gamboa (Eds.), BIODEVICES 2016 - 9th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016 (pp. 222-228). (BIODEVICES 2016 - 9th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016). SciTePress. https://doi.org/10.5220/0005772202220228

Montero-Rodŕiguez, Juan J. ; Salazar-Fĺorez, Edgar Eduardo ; Vega-Castillo, Paola et al. / An Impedance spectroscopy ASIC for low-frequency characterization of biological samples. BIODEVICES 2016 - 9th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016. editor / James Gilbert ; Haim Azhari ; Hesham Ali ; Carla Quintao ; Jan Sliwa ; Carolina Ruiz ; Ana Fred ; Hugo Gamboa. SciTePress, 2016. pp. 222-228 (BIODEVICES 2016 - 9th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016).

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title = "An Impedance spectroscopy ASIC for low-frequency characterization of biological samples",

abstract = "This paper describes the design and testing of an ASIC for impedance spectroscopy of biological samples at frequencies up to 40 kHz. The circuit is designed in the 350 nm AMS H35B4 technology and enables the measurement of impedances in the range of 10 kΩ up to 28 MΩ. The design features a digital oscillator and a current-to-voltage converter. The ASIC is used to monitor the growth of yeast cell cultures and porcine chondrocytes, in real-time, using a standard 384-well plate and copper electrodes.",

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doi = "10.5220/0005772202220228",

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series = "BIODEVICES 2016 - 9th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016",

publisher = "SciTePress",

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editor = "James Gilbert and Haim Azhari and Hesham Ali and Carla Quintao and Jan Sliwa and Carolina Ruiz and Ana Fred and Hugo Gamboa",

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Montero-Rodŕiguez, JJ, Salazar-Fĺorez, EE, Vega-Castillo, P, Tomasik, JM, Galjan, W, Hafkemeyer, KM & Krautschneider, W 2016, An Impedance spectroscopy ASIC for low-frequency characterization of biological samples. in J Gilbert, H Azhari, H Ali, C Quintao, J Sliwa, C Ruiz, A Fred & H Gamboa (eds), BIODEVICES 2016 - 9th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016. BIODEVICES 2016 - 9th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016, SciTePress, pp. 222-228, 9th International Conference on Biomedical Electronics and Devices, BIODEVICES 2016 - Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016, Rome, Italy, 21/02/16. https://doi.org/10.5220/0005772202220228

An Impedance spectroscopy ASIC for low-frequency characterization of biological samples. / Montero-Rodŕiguez, Juan J.; Salazar-Fĺorez, Edgar Eduardo; Vega-Castillo, Paola et al.
BIODEVICES 2016 - 9th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016. ed. / James Gilbert; Haim Azhari; Hesham Ali; Carla Quintao; Jan Sliwa; Carolina Ruiz; Ana Fred; Hugo Gamboa. SciTePress, 2016. p. 222-228 (BIODEVICES 2016 - 9th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AU - Montero-Rodŕiguez, Juan J.

AU - Salazar-Fĺorez, Edgar Eduardo

AU - Vega-Castillo, Paola

AU - Tomasik, Jakob M.

AU - Galjan, Wjatscheslaw

AU - Hafkemeyer, Kristian M.

AU - Krautschneider, Wolfgang

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N2 - This paper describes the design and testing of an ASIC for impedance spectroscopy of biological samples at frequencies up to 40 kHz. The circuit is designed in the 350 nm AMS H35B4 technology and enables the measurement of impedances in the range of 10 kΩ up to 28 MΩ. The design features a digital oscillator and a current-to-voltage converter. The ASIC is used to monitor the growth of yeast cell cultures and porcine chondrocytes, in real-time, using a standard 384-well plate and copper electrodes.

AB - This paper describes the design and testing of an ASIC for impedance spectroscopy of biological samples at frequencies up to 40 kHz. The circuit is designed in the 350 nm AMS H35B4 technology and enables the measurement of impedances in the range of 10 kΩ up to 28 MΩ. The design features a digital oscillator and a current-to-voltage converter. The ASIC is used to monitor the growth of yeast cell cultures and porcine chondrocytes, in real-time, using a standard 384-well plate and copper electrodes.

KW - ASIC

KW - Cell concentration

KW - Impedance spectroscopy

KW - Porcine chondrocytes

KW - Yeast

UR - https://www.scopus.com/pages/publications/84969884810

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DO - 10.5220/0005772202220228

M3 - Contribución a la conferencia

AN - SCOPUS:84969884810

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EP - 228

BT - BIODEVICES 2016 - 9th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016

A2 - Gilbert, James

A2 - Azhari, Haim

A2 - Ali, Hesham

A2 - Quintao, Carla

A2 - Sliwa, Jan

A2 - Ruiz, Carolina

A2 - Fred, Ana

A2 - Gamboa, Hugo

PB - SciTePress

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Montero-Rodŕiguez JJ, Salazar-Fĺorez EE, Vega-Castillo P, Tomasik JM, Galjan W, Hafkemeyer KM et al. An Impedance spectroscopy ASIC for low-frequency characterization of biological samples. In Gilbert J, Azhari H, Ali H, Quintao C, Sliwa J, Ruiz C, Fred A, Gamboa H, editors, BIODEVICES 2016 - 9th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016. SciTePress. 2016. p. 222-228. (BIODEVICES 2016 - 9th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016). doi: 10.5220/0005772202220228

An Impedance spectroscopy ASIC for low-frequency characterization of biological samples

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Keywords

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