Formulación de un prototipo de uso tópico a partir de extractos de fresa (Fragaria x ananassa., variedad Festival) ricos en antocianinas

Skin is the organ that provides primary protection to the body against the environment. However, skin impermeability limits the absorption and penetration of substances through the tissue layers in adequate quantities, making it difficult to treat skin lesions and diseases. Antioxidant phytochemicals represent an alternative source of new topic agents with bioactive potential. Red fruits, especially berries (strawberries, blackberries, raspberries), are of special interest due to their content in anthocyanin pigments, which have strong antioxidant and anti-inflammatory potential. Regarding strawberry, numerous studies have shown its benefits for human health; However, most studies have focused on studying strawberry fruit, while the rest of the plant has been widely overlooked. Furthermore, it has been shown that polyphenol content might be higher in plant leaves and stems than in the fruit (e.g. in blackberry and grapevine). The present proposal aims to examine the phytochemical profile of strawberry plant leaves from the northern zone of Cartago, and to compare it with strawberry seedlings grown in vitro. The objective is to identify the optimal growing conditions for eliciting greater anthocyanin production in the plants, and to use them to formulate a prototype topical formulation with potential biomedical applications, which will be evaluated in vitro skin models.

Desarrollar un prototipo natural de uso tópico con potencial aplicación biomédica basado en extractos ricos en antocianinas extraídas de fresas (Fragaria x ananassa, variedad Festival)

Áreas de Investigación Escuela de Biología: Biotecnología Vegetal y Aplicaciones Biomédicas