Espectrometría de masas de alta resolución en la evaluación de la presencia de plaguicidas carbamatos y sus derivados metabólicos en matrices ambientales acuosas mediante metodologías de análisis no dirigido y dirigido

Carbamates are a family of agrochemicals with insecticidal action widely used in crops in the northern area of Cartago,
where more than 70% of the vegetables consumed in Costa Rica are produced. Their availability in the market and use is
not regulated based on scientific principles that consider their fate in the environment after being applied to crops, nor their
persistence or the generation of metabolic degradation products. Costa Rica's drinking water quality regulation No. 38924-
S establishes a maximum of 0.1 micrograms/liter for mother molecules but does not regulate the presence of metabolites.
Like other organic molecules, carbamate's environmental depletion is limited, among other causes, due to their half-life,
solubility, partition coefficient, and microbiological activity in soil and water. It is known that the degradation of carbamates
can produce metabolites that could have higher toxicity than precursor molecules, so it is necessary to evaluate the
presence of carbamates and their metabolites in environmental matrices using unconventional techniques. In this project,
the presence of carbamates will be evaluated using high-resolution mass spectrometry technology to identify carbamates
and their metabolites present in environmental aqueous matrices, implementing methodologies of non-targeted analysis
and targeted analysis in groundwater samples from springs near agricultural areas of the country, in order to generate
relevant information for the control and environmental monitoring of these substances at the national level.

Evaluar la presencia de carbamatos y sus derivados metabólicos en matrices ambientales acuosas

Monitorieo de contaminantes ambientales