Personal profile
Research Interests
Carolina Centeno-Cerdas is a Costa Rican scientist and professor specializing in biotechnology, tissue engineering, and regenerative medicine. She holds a Bachelor’s degree in Biotechnology Engineering from the Instituto Tecnológico de Costa Rica (TEC), a Master’s degree in Biomedical Sciences with emphasis in Cellular Physiology from the University of Costa Rica (UCR), and a Doctoral degree in Experimental Medicine from the Technical University of Munich, Germany.
She is a Full Tenure Professor at TEC’s School of Biology and a researcher at the Center for Research in Biotechnology (CIB), where she coordinates the Tissue Engineering Laboratory (Laintec). Her academic and research career spans more than two decades, focusing on clinical and preclinical studies in molecular diagnostics, bioactivity, regenerative therapies, and tissue engineering.
Currently, Dr. Centeno-Cerdas works on the development of more robust and ethical study models, such as organ-on-chip systems, and conducts bioactivity and biocompatibility testing to evaluate new biomedical applications. More recently, her research has expanded into the use of bioprinting techniques to design innovative solutions for tissue regeneration and personalized medicine.
Education/Academic qualification
Bachelor, Bachelor’s degree in Biotechnology Engineering from the Costa Rica Institute of Technology (TEC)
Master, Master’s degree in Biomedical Sciences with emphasis in Cellular Physiology from the University of Costa Rica (UCR)
Doctoral degree in Experimental Medicine from the Technical University of Munich (TUM), Germany
Fields of knowledge of Science and Technology according to the OECD Frascati Manual
- Medical and Health Sciences
- Engineering and Technology
Campus del Instituto Tecnológico de Costa Rica
- CAMPUS TECNOLOGICO CENTRAL CARTAGO
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Plataforma Integral para la Fabricación, Evaluación y Comercialización de Andamios Óseos Personalizados con Biomateriales Avanzados: De la Impresión 3D al Modelo Animal (FI-006N-25)
Centeno Cerdas, C. (Coordinating Researcher (may be from TEC or another entity)) & Lesser-Rojas, L. (Institutional academic coordinator)
1/01/26 → 31/12/27
Project: Research Projects With national external funds › Technological Development
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INNOrganic: INNovation in ORGANIC study models for preclinical testing Fase I (GI)*: Prueba de concepto en la modelación de un sistema digestivo in vitro en un sistema organ-on-a-chip * GI: Gastrointestinal
Centeno Cerdas, C. (Institutional academic coordinator), Calvo-Castro, L. A. (Institutional academic coordinator), Quirós Solano, W. (Institutional academic coordinator) & Vargas, E. (Institutional academic coordinator)
1/01/23 → 31/12/25
Project: Research Projects Internally funded › Basic and applied research
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Papp Fase I: Establecimiento de un modelo intestinal in vitro para el cálculo del coeficiente de permeabilidad aparente de compuestos bioactivos
Salas Arias, K. (Institutional academic coordinator), Calvo-Castro, L. A. (Institutional academic coordinator), Centeno Cerdas, C. (Institutional academic coordinator) & Jiménez Quesada, K. (Institutional academic coordinator)
1/01/22 → 30/06/23
Project: Research Projects Internally funded › Basic and applied research
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Evaluación de un sistema biológico eucariota (Nicotiana tabacum) para la producción de insulina humana recombinante, con miras al escalamiento en biorreactor
Sánchez Calvo, L. (External collaborating researcher ), Ramírez Castro, M. (Institutional academic coordinator), Centeno Cerdas, C. (Institutional academic coordinator) & Garcia-Gomez, D. (Institutional academic coordinator)
1/01/20 → 31/12/21
Project: Research Projects Internally funded › Basic and applied research
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Advancements in Surface Modification and Bioactive Coatings for Organ-on-Chip Technologies
Centeno-Cerdas, C., Ramirez-Gonzalez, G. A., Consumi-Tubito, C. & Vargas-Mendez, E., 1 Dec 2025, In: Tissue Engineering Part A. 31, 23-24, 1 p.Research output: Contribution to journal › Meeting Abstract › peer-review
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Advancing Organ-on-a-Chip Systems: The Role of Scaffold Materials and Coatings in Engineering Cell Microenvironment
Ramírez-González, G. A., Consumi-Tubito, C., Vargas-Méndez, E. & Centeno-Cerdas, C., May 2025, In: Polymers. 17, 9, 1263.Research output: Contribution to journal › Review article › peer-review
Open Access4 Scopus citations -
Preliminary evaluation of a scalable eukaryotic biological system (Nicotiana tabacum) to produce recombinant human insulin
Centeno-Cerdas, C., Jimenez-Rojas, A., Echeverria-Beirute, F. & Jarquin-Cordero, M., 2025, In: Tecnologia En Marcha. 39, 1, p. 56-73 18 p.Research output: Contribution to journal › Article › peer-review
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Composites of Polylactic Acid with Diatomaceous Earth for 3D-Printing Biocompatible Scaffolds: A Systematic Study of Their Mechanical, Thermal, and Biocompatibility Properties
Trejos-Soto, L., Rivas-Hernández, G. O., Mora-Bolaños, R., Vargas-Valverde, N., Valerio, A., Ulloa-Fernández, A., Oviedo-Quirós, J., García-Piñeres, A., Paniagua, S. A., Centeno-Cerdas, C. & Lesser-Rojas, L., Nov 2024, In: Bioengineering. 11, 11, 1059.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Procesamiento y esterilización de tejido óseo para su uso terapéutico: bases preclínicas desde una universidad tecnológica
Centeno-Cerdas, C., Somarribas-Brenes, F., Vargas-Segura, W., Jarquin-Cordero, M., Ulloa-Fernandez, A. & Calvo-Castro, L. A., 29 Nov 2024, In: Revista Tecnología en Marcha. 37, p. 215-228 14 p.Research output: Contribution to journal › Article › peer-review